Risk Factors for Loss to Follow-up During Active Surveillance of Patients with Stage I Seminoma

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Randomized trials in 2466 patients with stage I seminoma: patterns of relapse and follow-up.

BACKGROUND From July 1, 1989, through March 31, 2001, 2466 patients with stage I seminoma were evaluated in three randomized noninferiority trials: the TE10, TE18, and TE19 trials. We analyzed mature results of these studies. METHODS The TE10 trial randomly assigned 478 patients to para-aortic and ipsilateral iliac lymph node (dogleg field) or para-aortic only radiation therapy (total dose = ...

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Surveillance in stage I seminoma patients: a long-term assessment.

BACKGROUND Following orchidectomy patients with stage I seminoma of the testis may be managed by either surveillance or adjuvant treatment. In view of the very high cure rate, it is important to analyse long-term outcomes. OBJECTIVE To provide data to advise patients on treatment burden and risk of recurrence associated with surveillance. DESIGN, SETTING, AND PARTICIPANTS We audited the cas...

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[Surveillance after orchiectomy for stage I testicular seminoma].

The results of treatment by orchiectomy and radiotherapy for stage I testicular seminoma are excellent with cure rates exceeding 95% and relapse rates less than 5%. However, after the development of successful surveillance programs for stage I nonseminomatous testicular cancers, the role of radiotherapy has been questioned by some authors and they proposed a "surveillance policy" for these pati...

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Prognostic factors for tumor recurrence in patients with clinical stage I seminoma undergoing surveillance—protocol for a systematic review

BACKGROUND Testicular cancer is primarily treated with the surgical removal of the affected testis. About 50% of testicular cancer patients present with a stage I seminoma. If no chemo- or radiotherapy as adjuvant treatment is initiated after orchiectomy, 15-20% of these patients will develop metastases. Although adjuvant treatment is effective in reducing the relapse risk, there is rising conc...

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Evaluation of a prognostic model for risk of relapse in stage I seminoma surveillance

A prognostic model for relapse risk in stage I seminoma managed by surveillance after orchiectomy has been developed but has not been independently validated. Individual data on 685 stage I seminoma surveillance patients managed between 1998 and 2005 at three cancer centers were retrospectively analyzed. Variables including age and pathology of the primary tumor: small vessel invasion, tumor si...

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ژورنال

عنوان ژورنال: Japanese Journal of Clinical Oncology

سال: 2014

ISSN: 0368-2811,1465-3621

DOI: 10.1093/jjco/hyu001